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Enrofloxacin

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Brands

Baytril

 

Description

A member of the fluoroquinolone anitbiotics, it has a broad spectrum of antibacterial activity that is great against gram-negative bacteria and good against some gram-positive bacteria and Mycoplasma.

Fluoroquinolones work by deactivating bacterial enzymes necessary for the
transcription of DNA.  DNA is very tightly coiled in order to fit inside a
cell.  Segments to be used must be uncoiled by an enzyme called DNA gyrase. The fluoroquinolone antibiotic deactivates DNA gyrase making the reading of DNA impossible.  The bacterial cell dies.

 

Uses

  • Mycoplasma
  • Staphylococci
  • Urinary tract infections
  • Soft tissue injury

 

Dosage

  • 10 mg/kg orally, twice daily (24)
  • 100 mg/liter in drinking water (24)
  • 5 mg/lb orally, twice daily (7)
  • 0.2 ml/lb orally for 14 to 30 days (7)
  • 2.5-5.0 mg/kg orally or by injections, twice daily (20)

 

Side Effects

  • Seizures
  • Diarrhea
  • Itching, redness, soreness at injection site

 

Combinations

Doxycycline

 

Incompatibilities

Theophylline

 

References: [7] [19] [20] [21] [22] [24]

Wed, 12/05/2007 - 08:15 — admin

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