Synonyms

Prednisolone - Prednisolone Sodium Succinate; Prednisolone Acetate

 

Description

Prednisone and Prednisolone are both members of the glucocorticoid class of hormones.  They are used to treat a variety of conditions that involve inflammation.

Prednisone is activated by the patient's liver into prednisolone.

These medications are considered to be interchangeable.

 

Uses

• Inner ear infections, wry neck
• Pituitary tumours
• Respiratory disorders such as pneumonia
• Severe itching
• In treating shock to improve circulation
• Pneumonia
• Inner ear infection/wryneck
• Injury
• Pituitary tumours

 

Dosage

• 0.25 to 1mg/lb SID, PO (7)
• Oral Solution 1mg/mL - 0.25 to 1cc/lb (7)
• 0.5-0.22 mg by injection (20)

 

Side Effects

• Cataracts
• Glaucoma
• Delayed wound healing
• Excessive thirst and excessive urination
• Atrophy at injection site

 

Warnings

• Can depress the immune system over time, so do not over do the length of the dosage.
• Glucocorticoid hormones can cause abortion in pregnant patients. They should not be used in pregnancy. (21)

 

Incompatibilities

NSAIDs, eg. Aspirin

 

References: [7] [14] [20] [21]

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